UNC5D Antibody

CAT: 0223-56-833Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-56-833Size:400 µL
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Background
UNC5D is receptor for netrin. May be involved in axon guidance by mediating axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand (By similarity) .
NCBI Gene ID
137970
Swiss Prot
Q6UXZ4
Accession Number
Q6UXZ4
Host
Rabbit
Reactivity
Human
Immunogen
This UNC5D antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 483-511 amino acids from the Central region of human UNC5D.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
106 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
UNC5D
NCBI Official Name
Netrin receptor UNC5D
NCBI Organism
Homo sapiens
Background Reference 01
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 02
Wang, H., et al. Biochem. Biophys. Res. Commun. 370 (4) :594-598 (2008)
Background Reference 03
Choy, K.W., et al. Physiol. Genomics 25 (1) :9-15 (2006)
Background Reference 04
Zhong, Y., et al. Cereb. Cortex 14 (10) :1144-1152 (2004)
Other Product Names
Netrin receptor UNC5D, Protein unc-5 homolog 4, Protein unc-5 homolog D, UNC5D, KIAA1777, UNC5H4
Tested Applications
WB
Protein ID
54036576
Physical Properties
Liquid

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