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TWA1 Antibody

CAT: 0223-5305-01Size: 0.02 mgDry Ice: NoHazardous: No
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CAT#:0223-5305-01Size:0.02 mg
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Background
TWA1 Antibody: TWA1 was identified through a two hybrid-associated protein screen with RanBPM. TWA1 is well conserved through evolution and is localized within the nucleus. It interacts with RanBP9 and comprises a protein complex with RanBPM and Muskelin. TWA1 was found to possess the LisH-CTLH motif which is detected in proteins involved in microtubule dynamics, cell migration, nucleokinesis and chromosome segregation. These functions overlap with functions suggested for the RanGTPase cycle. Recent findings suggested that there is an as yet uncovered function of the RanGTPase cycle.
NCBI Gene ID
54994
Swiss Prot
Q9NWU2
Accession Number
NP_060366
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Homeostasis
Purification
TWA1 Antibody is affinity chromatography purified via peptide column.
Positive Control
Cat. No. 1303 - Human Brain Tissue Lysate
Concentration
1 mg/mL
Homology
Predicted species reactivity based on immunogen sequence: Chicken: (100%), Bovine: (100%)
Buffer
TWA1 Antibody is supplied in PBS containing 0.02% sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
TWA1 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Fragment
IgG
Symbol
GID8
NCBI Official Name
Chromosome 20 open reading frame 11
NCBI Organism
Homo sapiens
Background Reference 01
Umeda M, Nishitani H, and Nishimoto T. A novel nuclear protein, Twa1, and Muskelin comprise a complex with RanBPM. Gene2003; 303:47-54.
Background Reference 02
Kobayashi N, Yang J, Ueda A, et al. RanBPM, Muskelin, p48EMLP, p44CTLH, and the armadillo-repeat proteins ARMC8alpha and ARMC8beta are components of the CTLH complex. Gene2007; 396:236-47.
Other Product Names
TWA1 Antibody: TWA1, C20orf11, Glucose-induced degradation protein 8 homolog, Two hybrid-associated protein 1 with RanBPM, Twa1
Tested Applications
ELISA, WB, IHC-P, IF
Protein ID
8923557
Physical Properties
Liquid

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