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RASGRF1 Antibody

CAT: 0223-63-012Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-63-012Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
RASGRF1 is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25 gene product. Functional analysis has demonstrated that this protein stimulates the dissociation of GDP from RAS protein. Studies of the similar gene in mouse suggested that the Ras-GEF activity of this protein in brain can be activated by Ca2+ influx, muscarinic receptors, and G protein beta-gamma subunit. Mouse studies also indicated that the Ras-GEF signaling pathway mediated by this protein may be important for long-term memory.
NCBI Gene ID
5923
Swiss Prot
Q13972
Accession Number
Q13972
Host
Rabbit
Reactivity
Human
Immunogen
This RASGRF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 907-936 amino acids from human RASGRF1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
145 kDa
Fragment
Rabbit Ig
Symbol
RASGRF1
NCBI Official Name
Ras-specific guanine nucleotide-releasing factor 1
NCBI Organism
Homo sapiens
Background Reference 01
Iguchi, T., Int. J. Oncol. 31 (2), 285-291 (2007)
Background Reference 02
Holmes, R., Mol. Cell. Biol. 26 (24), 9564-9570 (2006)
Other Product Names
Ras-specific guanine nucleotide-releasing factor 1, Ras-GRF1, Guanine nucleotide-releasing protein, GNRP, Ras-specific nucleotide exchange factor CDC25, RASGRF1, CDC25, GNRP, GRF1
Tested Applications
WB, IHC-P
Protein ID
13124259
Physical Properties
Liquid

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CatalogName
GWB-MU371BRASGRF1 Antibody

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