RASGRP3 Antibody

• Background:

  The protein encoded by this gene is a guanine nucleotide exchange factor that activates the oncogenes HRAS and RAP1A. Defects in this gene have been associated with systemic lupus erythematosus and several cancers.

• NCBI Gene ID:

  25780

• Swiss Prot:

  Q8IV61

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 540-689 of human RASGRP3 (NP_056191.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Immunology, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  BT-474

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 78kDa

• Fragment:

  IgG

• Symbol:

  RASGRP3

• Positive Control 2:

  A-549

• Positive Control 3:

  Mouse heart

• Positive Control 4:

  Mouse lung

• Positive Control 5:

  Mouse thymus

• NCBI Official Name:

  RAS guanyl releasing protein 3

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  GRP3, ras guanyl-releasing protein 3, CalDAG-GEFIII, RAS guanyl releasing protein 3 (calcium and DAG-regulated), calcium and DAG-regulated guanine nucleotide exchange factor III, calcium- and diacylglycerol-regulated guanine nucleotide exchange factor III, guanine nucleotide exchange factor for Rap1

• Tested Applications:

  WB, IF

• Physical Properties:

  Liquid