CDC2 Antibody

CAT: 0223-62-963Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-62-963Size:400 µL
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
CDK1 is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control.
NCBI Gene ID
983
Swiss Prot
P06493
Accession Number
P06493
Host
Rabbit
Reactivity
Human
Immunogen
This CDC2 (CDK1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 230-260 amino acids from the C-terminal region of human CDC2 (CDK1) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Neuroscience
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
34 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
CDK1
NCBI Official Name
Cyclin-dependent kinase 1
NCBI Organism
Homo sapiens
Background Reference 01
Chow, J.P., et al., J. Biol. Chem. 278 (42) :40815-40828 (2003) .
Background Reference 02
Nozoe, T., et al., J. Cancer Res. Clin. Oncol. 129 (9) :498-502 (2003) .
Background Reference 03
Margottin-Goguet, F., et al., Dev. Cell 4 (6) :813-826 (2003) .
Background Reference 04
Yuan, H., et al., J. Virol. 77 (3) :2063-2070 (2003) .
Other Product Names
Cyclin-dependent kinase 1, CDK1, Cell division control protein 2 homolog, Cell division protein kinase 1, p34 protein kinase, CDK1, CDC2, CDC28A, CDKN1, P34CDC2
Tested Applications
WB
Protein ID
334302921
Physical Properties
Liquid

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