CDC2 (Ab 19) Antibody

• Background:

  Plays a key role in the control of the eukaryotic cell cycle. It is required in higher cells for entry into S-phase and mitosis. p34 is a component of the kinase complex that phosphorylates the repetitive C-terminus of RNA polymerase II.

• NCBI Gene ID:

  983

• Swiss Prot:

  P06493

• Accession Number:

  NP_001163877.1

• Host:

  Rabbit

• Reactivity:

  Human, Rat

• Immunogen:

  CDC2 (Ab-19) antibody was raised against a peptide sequence around aa.17~21 (V-V-Y-K-G) derived from Human CDC2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Apoptosis, Cancer, Cell Cycle

• Purification:

  Antibodies were purified by affinity-chromatography using epitope-specific peptide.

• Concentration:

  1 mg/mL

• Buffer:

  Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store antibody at -20˚ C for up to one year.

• Calculated Molecular Weight:

  34 kDa

• Specificity:

  This antibody detects endogenous level of total CDC2 protein.

• Applications Notes:

  Immunohistochemistry: 1:50~1:100

• Symbol:

  CDK1

• NCBI Official Name:

  Cyclin-dependent kinase 1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Hunter, T. (1995) Cell 80, 225-236. Wells, N. J. et al. (1999) J. Cell. Sci. 112, 3361-3371. McGowan, C. H. and Russell, P. (1993) EMBO J. 12, 75-85.

• Other Product Names:

  CDC2, CDC28A, P34CDC2, CDC28, CDC2A, CDK1, Cyclin-dependent kinase 1

• Tested Applications:

  IHC

• Protein ID:

  281427278

• Physical Properties:

  Liquid