CDC2 (Ab 19) Antibody

• Background :

  Plays a key role in the control of the eukaryotic cell cycle. It is required in higher cells for entry into S-phase and mitosis. p34 is a component of the kinase complex that phosphorylates the repetitive C-terminus of RNA polymerase II.

• NCBI Gene ID :

  983

• Swiss Prot :

  P06493

• Accession Number :

  NP_001163877.1

• Host :

  Rabbit

• Reactivity :

  Human, Rat

• Immunogen :

  CDC2 (Ab-19) antibody was raised against a peptide sequence around aa.17~21 (V-V-Y-K-G) derived from Human CDC2.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Apoptosis, Cancer, Cell Cycle

• Purification :

  Antibodies were purified by affinity-chromatography using epitope-specific peptide.

• Concentration :

  1 mg/mL

• Buffer :

  Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store antibody at -20˚ C for up to one year.

• Calculated Molecular Weight :

  34 kDa

• Specificity :

  This antibody detects endogenous level of total CDC2 protein.

• Applications Notes :

  Immunohistochemistry: 1:50~1:100

• Symbol :

  CDK1

• NCBI Official Name :

  Cyclin-dependent kinase 1

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Hunter, T. (1995) Cell 80, 225-236. Wells, N. J. et al. (1999) J. Cell. Sci. 112, 3361-3371. McGowan, C. H. and Russell, P. (1993) EMBO J. 12, 75-85.

• Other Product Names :

  CDC2, CDC28A, P34CDC2, CDC28, CDC2A, CDK1, Cyclin-dependent kinase 1

• Tested Applications :

  IHC

• Protein ID :

  281427278

• Physical Properties :

  Liquid