CDC7 Antibody

• Background:

  This gene encodes a cell division cycle protein with kinase activity that is critical for the G1/S transition. The yeast homolog is also essential for initiation of DNA replication as cell division occurs. Overexpression of this gene product may be associated with neoplastic transformation for some tumors. Multiple alternatively spliced transcript variants that encode the same protein have been detected.

• NCBI Gene ID:

  8317

• Swiss Prot:

  O00311

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 275-574 of human CDC7 (NP_001127892.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  SH-SY5Y

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 70kDa

• Fragment:

  IgG

• Applications Notes:

  WB: 1:500 - 1:2000

• Symbol:

  CDC7

• Positive Control 2:

  HepG2

• Positive Control 3:

  THP-1

• NCBI Official Name:

  Cell division cycle 7

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  CDC7L1, HsCDC7, Hsk1, huCDC7, cell division cycle 7-related protein kinase, CDC7 (cell division cycle 7, S. cerevisiae, homolog) -like 1, CDC7-related kinase, cell division cycle 7 homolog, cell division cycle 7-like protein 1, epididymis secretory sperm binding protein

• Tested Applications:

  WB

• Physical Properties:

  Liquid