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MAPK11 Antibody

CAT: 0223-62-738Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-62-738Size:400 µL
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
MAPK11 is a Ser/Thr kinase involved in a signal transduction pathway that is activated by changes in the osmolarity of the extracellular environment, by cytokines, or by environmental stress. It preferentially phosphorylates transcription factor ATF2. This protein is activated by phosphorylation on threonine and tyrosine by MKK6, and is inhibited by pyridinyl-imidazole related compounds. Highest expression levels are in the brain and heart, with additional expression in the placenta, lung, liver, skeletal muscle, kidney and pancreas.
NCBI Gene ID
5600
Swiss Prot
Q15759
Accession Number
Q15759
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This MAPK11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 334-366 amino acids from the center region of human MAPK11.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
41 kDa
Fragment
Rabbit Ig
Symbol
MAPK11
NCBI Official Name
Mitogen-activated protein kinase 11
NCBI Organism
Homo sapiens
Background Reference 01
Strausberg, R.L., et al., Proc. Natl. Acad. Sci. U.S.A. 99 (26) :16899-16903 (2002) .
Background Reference 02
Dunham, I., et al., Nature 402 (6761) :489-495 (1999) .
Background Reference 03
Enslen, H., et al., J. Biol. Chem. 273 (3) :1741-1748 (1998) .
Background Reference 04
Kumar, S., et al., Biochem. Biophys. Res. Commun. 235 (3) :533-538 (1997) .
Other Product Names
Mitogen-activated protein kinase 11, MAP kinase 11, MAPK 11, Mitogen-activated protein kinase p38 beta, MAP kinase p38 beta, p38b, Stress-activated protein kinase 2b, SAPK2b, p38-2, MAPK11, PRKM11, SAPK2, SAPK2B
Tested Applications
WB, IHC-P
Protein ID
134047835
Physical Properties
Liquid

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F40152-0.08MLMAPK11 Antibody

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