MAPK12 Antibody

• Background:

  P38 gamma is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. Activation of members of the mitogen-activated protein kinase family is a major mechanism for transduction of extracellular signals. Stress-activated protein kinases are one subclass of MAP kinases. P38 gamma functions as a signal transducer during differentiation of myoblasts to myotubes.

• NCBI Gene ID:

  6300

• Swiss Prot:

  P53778

• Accession Number:

  P53778

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This MAPK12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 336-367 amino acids from the C-terminal region of human MAPK12.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle, Signal Transduction

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  42 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  MAPK12

• NCBI Official Name:

  Mitogen-activated protein kinase 12

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Garcia-Lora, A., et al., Cancer Immunol. Immunother. 52 (1) :59-64 (2003) .

• Background Reference 02:

  Julien, C., et al., J. Biol. Chem. 278 (43) :42615-42624 (2003) .

• Background Reference 03:

  Robinson, M.J., et al., J. Biol. Chem. 277 (7) :5094-5100 (2002) .

• Background Reference 04:

  Court, N.W., et al., J. Mol. Cell. Cardiol. 34 (4) :413-426 (2002) .

• Other Product Names:

  Mitogen-activated protein kinase 12, MAP kinase 12, MAPK 12, Extracellular signal-regulated kinase 6, ERK-6, Mitogen-activated protein kinase p38 gamma, MAP kinase p38 gamma, Stress-activated protein kinase 3, MAPK12, ERK6, SAPK3

• Tested Applications:

  WB, IHC-P

• Protein ID:

  2851522

• Physical Properties:

  Liquid