MAPK10 Antibody

• Background:

  The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as integration points for multiple biochemical signals and are involved in a wide variety of cellular processes, such as proliferation, differentiation, transcription regulation and development. This kinase is specifically expressed in a subset of neurons in the nervous system and is activated by threonine and tyrosine phosphorylation. Targeted deletion of this gene in mice suggests that it may have a role in stress-induced neuronal apoptosis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. A recent study provided evidence for translational readthrough in this gene and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon.

• NCBI Gene ID:

  5602

• Swiss Prot:

  P53779

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant protein of human MAPK10.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Apoptosis, Cancer, Cell Cycle, Immunology, Neuroscience, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  Mouse testis

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 52kDa

• Fragment:

  IgG

• Symbol:

  MAPK10

• Positive Control 2:

  Rat testis

• NCBI Official Name:

  Mitogen-activated protein kinase 10

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  JNK3, JNK3A, PRKM1SAPK1b, p493F12, p54bSAPK, mitogen-activated protein kinase 1JNK3 alpha protein kinase, MAP kinase 1MAP kinase p49 3F12, c-Jun N-terminal kinase 3, stress activated protein kinase beta, stress-activated protein kinase 1b, stress-activated protein kinase JNK3

• Tested Applications:

  WB, IF

• Physical Properties:

  Liquid