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MAPK10 Antibody

CAT: 0223-16-937Size: 100 µLDry Ice: NoHazardous: No
CAT#:0223-16-937Size:100 µL
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as integration points for multiple biochemical signals and are involved in a wide variety of cellular processes, such as proliferation, differentiation, transcription regulation and development. This kinase is specifically expressed in a subset of neurons in the nervous system and is activated by threonine and tyrosine phosphorylation. Targeted deletion of this gene in mice suggests that it may have a role in stress-induced neuronal apoptosis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. A recent study provided evidence for translational readthrough in this gene and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon.
NCBI Gene ID
5602
Swiss Prot
P53779
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein of human MAPK10.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Apoptosis, Cancer, Cell Cycle, Immunology, Neuroscience, Signal Transduction
Purification
Affinity purification
Positive Control
Mouse testis
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 52kDa
Fragment
IgG
Symbol
MAPK10
Positive Control 2
Rat testis
NCBI Official Name
Mitogen-activated protein kinase 10
NCBI Organism
Homo sapiens
Other Product Names
JNK3, JNK3A, PRKM1SAPK1b, p493F12, p54bSAPK, mitogen-activated protein kinase 1JNK3 alpha protein kinase, MAP kinase 1MAP kinase p49 3F12, c-Jun N-terminal kinase 3, stress activated protein kinase beta, stress-activated protein kinase 1b, stress-activated protein kinase JNK3
Tested Applications
WB, IF
Physical Properties
Liquid

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