MAPK14 Antibody

CAT: 0223-56-459Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-56-459Size:400 µL
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response. Four alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
NCBI Gene ID
1432
Swiss Prot
Q16539
Accession Number
Q16539
Host
Rabbit
Reactivity
Human
Immunogen
This MAPK14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 158-192 amino acids from the Central region of human MAPK14.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Immunology, Neuroscience, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Zebrafish, Mouse, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
41 kDa
Fragment
Rabbit Ig
Symbol
MAPK14
NCBI Official Name
Mitogen-activated protein kinase 14
NCBI Organism
Homo sapiens
Background Reference 01
Pan, W.W., et al. J. Biol. Chem. 285 (45) :34348-34354 (2010) Marchant, D., et al. J. Virol. 84 (21) :11359-11373 (2010) Arana-Argaez, V.E., et al. J. Biol. Chem. 285 (43) :32824-32833 (2010) Ferreiro, I., et al. J. Biol. Chem. 285 (41) :31819-31828 (2010) Tang, P., et al. Zhonghua Gan Zang Bing Za Zhi 18 (8) :604-608 (2010)
Other Product Names
Mitogen-activated protein kinase 14, MAP kinase 14, MAPK 14, Cytokine suppressive anti-inflammatory drug-binding protein, CSAID-binding protein, CSBP, MAP kinase MXI2, MAX-interacting protein 2, Mitogen-activated protein kinase p38 alpha, MAP kinase p38 alpha, Stress-activated protein kinase 2a, SAPK2a, MAPK14, CSBP, CSBP1, CSBP2, CSPB1, MXI2, SAPK2A
Tested Applications
WB, IHC-P, IF
Physical Properties
Liquid

Related Products

CatalogName
16-907MAPK1/MAPK3 Antibody
16-735MAPK1/MAPK3 Antibody
62-958MAPK11 Antibody
62-961MAPK12 Antibody
16-937MAPK10 Antibody
27-020MAPK15 Antibody
22-984MAPK13 Antibody
23-126MAPK11 Antibody
62-738MAPK11 Antibody
62-960MAPK13 Antibody

Alternative Products

CatalogName
MBS8515947-01MAPK14 Antibody

Popular Products