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MAGEH1 Antibody

CAT: 0223-62-160Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-62-160Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Melanoma-associated antigen (MAGE) are completely silent in normal tissues, with the exception of male germ cells, and, for some of them, placenta. These antigens ought to be strictly tumor specific, expressed in tumor cells of various histological types. Because of their specific expression on tumor cells, these antigens are of particular interest for antitumor immunotherapy. Genes of the MAGE family direct the expression of tumor antigens that are recognized on a human melanoma by autologous cytolytic T lymphocytes. Though the function of MAGEH1 is not fully elucidated, it may play a role in embryonal development and tumor transformation or aspects of tumor progression.
NCBI Gene ID
28986
Swiss Prot
Q9H213
Accession Number
Q9H213
Host
Rabbit
Reactivity
Human
Immunogen
This MAGEH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 186-218 amino acids from the C-terminal region of human MAGEH1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
24 kDa
Fragment
Rabbit Ig
Symbol
MAGEH1
NCBI Official Name
Melanoma-associated antigen H1
NCBI Organism
Homo sapiens
Background Reference 01
Chomez, P., et al., Cancer Res. 61 (14) :5544-5551 (2001) .
Background Reference 02
Zhu, F., et al., BioTechniques 29 (2) :310-313 (2000) .
Other Product Names
Melanoma-associated antigen H1, Apoptosis-related protein 1, APR-1, MAGE-H1 antigen, Restin, MAGEH1, APR1
Tested Applications
WB, IHC-P
Protein ID
14423761
Physical Properties
Liquid

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