MAGEH1 Antibody

• Background:

  Melanoma-associated antigen (MAGE) are completely silent in normal tissues, with the exception of male germ cells, and, for some of them, placenta. These antigens ought to be strictly tumor specific, expressed in tumor cells of various histological types. Because of their specific expression on tumor cells, these antigens are of particular interest for antitumor immunotherapy. Genes of the MAGE family direct the expression of tumor antigens that are recognized on a human melanoma by autologous cytolytic T lymphocytes. Though the function of MAGEH1 is not fully elucidated, it may play a role in embryonal development and tumor transformation or aspects of tumor progression.

• NCBI Gene ID:

  28986

• Swiss Prot:

  Q9H213

• Accession Number:

  Q9H213

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This MAGEH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 186-218 amino acids from the C-terminal region of human MAGEH1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Mouse

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  24 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  MAGEH1

• NCBI Official Name:

  Melanoma-associated antigen H1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Chomez, P., et al., Cancer Res. 61 (14) :5544-5551 (2001) .

• Background Reference 02:

  Zhu, F., et al., BioTechniques 29 (2) :310-313 (2000) .

• Other Product Names:

  Melanoma-associated antigen H1, Apoptosis-related protein 1, APR-1, MAGE-H1 antigen, Restin, MAGEH1, APR1

• Tested Applications:

  WB, IHC-P

• Protein ID:

  14423761

• Physical Properties:

  Liquid