MAGED1 Antibody

• Background:

  This gene is a member of the melanoma antigen gene (MAGE) family. Most of the genes of this family encode tumor specific antigens that are not expressed in normal adult tissues except testis. Although the protein encoded by this gene shares strong homology with members of the MAGE family, it is expressed in almost all normal adult tissues. This gene has been demonstrated to be involved in the p75 neurotrophin receptor mediated programmed cell death pathway. Three transcript variants encoding two different isoforms have been found for this gene.

• NCBI Gene ID:

  9500

• Swiss Prot:

  Q9Y5V3

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 635-834 of human MAGED1 (NP_001005333.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Apoptosis, Cancer, Cell Cycle

• Purification:

  Affinity purification

• Positive Control:

  Mouse liver

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 86kDa

• Fragment:

  IgG

• Symbol:

  MAGED1

• Positive Control 2:

  Mouse lung

• Positive Control 3:

  Rat lung

• Positive Control 4:

  Rat liver

• NCBI Official Name:

  Melanoma-associated antigen D1

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  Melanoma-associated antigen D1, MAGE tumor antigen CCF, MAGE-D1 antigen, Neurotrophin receptor-interacting MAGE homolog, MAGED1, NRAGE

• Tested Applications:

  WB, IHC

• Physical Properties:

  Liquid