MAGED1 Antibody

• Background:

  MAGED1 is a member of the melanoma antigen gene (MAGE) family. Most of the genes of this family encode tumor specific antigens that are not expressed in normal adult tissues except testis. Although the protein encoded by this gene shares strong homology with members of the MAGE family, it is expressed in almost all normal adult tissues. This gene has been demonstrated to be involved in the p75 neurotrophin receptor mediated programmed cell death pathway.

• NCBI Gene ID:

  9500

• Swiss Prot:

  Q9Y5V3

• Accession Number:

  Q9Y5V3

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This MAGED1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 426-456 amino acids from the Central region of human MAGED1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Pig

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  86 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  MAGED1

• NCBI Official Name:

  Melanoma-associated antigen D1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Sasaki, A., et al., J. Biol. Chem. 277 (25) :22541-22546 (2002) .

• Background Reference 02:

  Kubu, C.J., et al., Genomics 70 (1) :150-152 (2000) .

• Background Reference 03:

  Salehi, A.H., et al., Neuron 27 (2) :279-288 (2000) .

• Background Reference 04:

  Pold, M., et al., Genomics 59 (2) :161-167 (1999) .

• Other Product Names:

  Melanoma-associated antigen D1, MAGE tumor antigen CCF, MAGE-D1 antigen, Neurotrophin receptor-interacting MAGE homolog, MAGED1, NRAGE

• Tested Applications:

  WB, IHC-P

• Protein ID:

  62906893

• Physical Properties:

  Liquid