ALG10B Antibody

• Background:

  Putative alpha-1,2-glucosyltransferase, which adds the third glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc (2) Man (9) GlcNAc (2) -PP-Dol. When coupled to KCNH2 may reduce KCNH2 sensitivity to classic proarrhythmic drug blockade, possibly by mediating glycosylation of KCNH2.

• NCBI Gene ID:

  144245

• Swiss Prot:

  Q5I7T1

• Accession Number:

  Q5I7T1

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This ALG10B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 324-353 amino acids from the C-terminal region of human ALG10B.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  55 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  ALG10B

• NCBI Official Name:

  Putative Dol-P-Glc:Glc (2) Man (9) GlcNAc (2) -PP-Dol alpha-1,2-glucosyltransferase

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Daly, A.K., et al. Nat. Genet. 41 (7) :816-819 (2009)

• Background Reference 02:

  Petersen, C.I., et al. Proc. Natl. Acad. Sci. U.S.A. 101 (32) :11773-11778 (2004)

• Background Reference 03:

  Kupershmidt, S., et al. FASEB J. 17 (15) :2263-2265 (2003)

• Other Product Names:

  Putative Dol-P-Glc:Glc (2) Man (9) GlcNAc (2) -PP-Dol alpha-1,2-glucosyltransferase, Alpha-1,2-glucosyltransferase ALG10-A, Alpha-2-glucosyltransferase ALG10-B, Asparagine-linked glycosylation protein 10 homolog B, Potassium channel regulator 1, ALG10B, KCR1

• Tested Applications:

  WB

• Protein ID:

  296434391

• Physical Properties:

  Liquid