ALG10B Antibody

• Background :

  Putative alpha-1,2-glucosyltransferase, which adds the third glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc (2) Man (9) GlcNAc (2) -PP-Dol. When coupled to KCNH2 may reduce KCNH2 sensitivity to classic proarrhythmic drug blockade, possibly by mediating glycosylation of KCNH2.

• NCBI Gene ID :

  144245

• Swiss Prot :

  Q5I7T1

• Accession Number :

  Q5I7T1

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  This ALG10B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 324-353 amino acids from the C-terminal region of human ALG10B.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Cell Cycle

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  55 kDa

• Fragment :

  Rabbit Ig

• Applications Notes :

  For WB starting dilution is: 1:1000

• Symbol :

  ALG10B

• NCBI Official Name :

  Putative Dol-P-Glc:Glc (2) Man (9) GlcNAc (2) -PP-Dol alpha-1,2-glucosyltransferase

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Daly, A.K., et al. Nat. Genet. 41 (7) :816-819 (2009)

• Background Reference 02 :

  Petersen, C.I., et al. Proc. Natl. Acad. Sci. U.S.A. 101 (32) :11773-11778 (2004)

• Background Reference 03 :

  Kupershmidt, S., et al. FASEB J. 17 (15) :2263-2265 (2003)

• Other Product Names :

  Putative Dol-P-Glc:Glc (2) Man (9) GlcNAc (2) -PP-Dol alpha-1,2-glucosyltransferase, Alpha-1,2-glucosyltransferase ALG10-A, Alpha-2-glucosyltransferase ALG10-B, Asparagine-linked glycosylation protein 10 homolog B, Potassium channel regulator 1, ALG10B, KCR1

• Tested Applications :

  WB

• Protein ID :

  296434391

• Physical Properties :

  Liquid