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ALG10B Antibody

CAT: 0223-61-992Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-61-992Size:400 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Putative alpha-1,2-glucosyltransferase, which adds the third glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc (2) Man (9) GlcNAc (2) -PP-Dol. When coupled to KCNH2 may reduce KCNH2 sensitivity to classic proarrhythmic drug blockade, possibly by mediating glycosylation of KCNH2.
NCBI Gene ID
144245
Swiss Prot
Q5I7T1
Accession Number
Q5I7T1
Host
Rabbit
Reactivity
Human
Immunogen
This ALG10B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 324-353 amino acids from the C-terminal region of human ALG10B.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
55 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
ALG10B
NCBI Official Name
Putative Dol-P-Glc:Glc (2) Man (9) GlcNAc (2) -PP-Dol alpha-1,2-glucosyltransferase
NCBI Organism
Homo sapiens
Background Reference 01
Daly, A.K., et al. Nat. Genet. 41 (7) :816-819 (2009)
Background Reference 02
Petersen, C.I., et al. Proc. Natl. Acad. Sci. U.S.A. 101 (32) :11773-11778 (2004)
Background Reference 03
Kupershmidt, S., et al. FASEB J. 17 (15) :2263-2265 (2003)
Other Product Names
Putative Dol-P-Glc:Glc (2) Man (9) GlcNAc (2) -PP-Dol alpha-1,2-glucosyltransferase, Alpha-1,2-glucosyltransferase ALG10-A, Alpha-2-glucosyltransferase ALG10-B, Asparagine-linked glycosylation protein 10 homolog B, Potassium channel regulator 1, ALG10B, KCR1
Tested Applications
WB
Protein ID
296434391
Physical Properties
Liquid

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