ALG10 Antibody

• Background:

  ALG10 encodes a membrane-associated protein that adds the third glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. That is, it transfers the terminal glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Glc2Man9GlcNAc (2) -PP-Dol. The rat protein homolog was shown to specifically modulate the gating function of the rat neuronal ether-a-go-go (EAG) potassium ion channel.

• NCBI Gene ID:

  84920

• Swiss Prot:

  Q5BKT4

• Accession Number:

  Q5BKT4

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This ALG10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 17-43 amino acids from the N-terminal region of human ALG10.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Mouse, Rat

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  56 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  ALG10

• NCBI Official Name:

  Dol-P-Glc:Glc (2) Man (9) GlcNAc (2) -PP-Dol alpha-1,2-glucosyltransferase

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Chapuis, J., et al. Mol. Psychiatry 14 (11) :1004-1016 (2009)

• Background Reference 02:

  Seshadri, S., et al. BMC Med. Genet.SUPPL 1, S15 (2007)

• Background Reference 03:

  Kupershmidt, S., et al. FASEB J. 17 (15) :2263-2265 (2003)

• Other Product Names:

  Dol-P-Glc:Glc (2) Man (9) GlcNAc (2) -PP-Dol alpha-1,2-glucosyltransferase, Alpha-1,2-glucosyltransferase ALG10-A, Alpha-2-glucosyltransferase ALG10-A, Asparagine-linked glycosylation protein 10 homolog A, ALG10, ALG10A

• Tested Applications:

  WB, IHC-P

• Protein ID:

  74736030

• Physical Properties:

  Liquid