HSD17B2 Antibody

• Background:

  HSD17B2 is capable of catalyzing the interconversion of testosterone and androstenedione, as well as estradiol and estrone.HSD17B2 also has 20-alpha-HSD activity. HSD17B2 uses NADH while EDH17B3 uses NADPH.

• NCBI Gene ID:

  3294

• Swiss Prot:

  P37059

• Accession Number:

  P37059

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This HSD17B2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 265-294 amino acids from the Central region of human HSD17B2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  43 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  HSD17B2

• NCBI Official Name:

  Estradiol 17-beta-dehydrogenase 2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Shen, Z., et al. Endocrinology 150 (11) :4941-4949 (2009)

• Background Reference 02:

  Bhavani, V., et al. Cancer Biomark 5 (4) :207-213 (2009)

• Background Reference 03:

  Olsen, J.V., et al. Cell 127 (3) :635-648 (2006)

• Other Product Names:

  Estradiol 17-beta-dehydrogenase 2, 17-beta-hydroxysteroid dehydrogenase type 2, 17-beta-HSD 2, 20 alpha-hydroxysteroid dehydrogenase, 20-alpha-HSD, E2DH, Microsomal 17-beta-hydroxysteroid dehydrogenase, Testosterone 17-beta-dehydrogenase, HSD17B2, EDH17B2

• Tested Applications:

  WB, IHC-P, Flow

• Protein ID:

  544152

• Physical Properties:

  Liquid