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HSD17B6 Antibody

CAT: 0223-29-593Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-29-593Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
HSD17B6 has both oxidoreductase and epimerase activities and is involved in androgen catabolism. The oxidoreductase activity can convert 3 alpha-adiol to dihydrotestosterone, while the epimerase activity can convert androsterone to epi-androsterone. Both reactions use NAD+ as the preferred cofactor. HSD17B6 is a member of the retinol dehydrogenase family.The protein encoded by this gene has both oxidoreductase and epimerase activities and is involved in androgen catabolism. The oxidoreductase activity can convert 3 alpha-adiol to dihydrotestosterone, while the epimerase activity can convert androsterone to epi-androsterone. Both reactions use NAD+ as the preferred cofactor. This gene is a member of the retinol dehydrogenase family. Transcript variants utilizing alternative polyadenylation signals exist.
NCBI Gene ID
8630
Swiss Prot
O14756
Accession Number
NP_003716
Host
Rabbit
Reactivity
Human, Mouse, Dog
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human HSD17B6.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Antibody is purified by protein A chromatography method.
Positive Control
A172 Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store HSD17B6 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
35 kDa
Applications Notes
HSD17B6 antibody can be used for detection of HSD17B6 by ELISA at 1:62500. HSD17B6 antibody can be used for detection of HSD17B6 by western blot at 1.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
HSD17B6
NCBI Official Name
Hydroxysteroid (17-beta) dehydrogenase 6
NCBI Organism
Homo sapiens
Background Reference 01
Huang, X.F. (2001) Biochim. Biophys. Acta 1520 (2), 124-130.
Other Product Names
HSD17B6, HSE, RODH, SDR9C6
Tested Applications
ELISA, WB, IHC
Protein ID
19743808
Physical Properties
Liquid

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