HSD17B1 Antibody

• Background:

  Favors the reduction of estrogens and androgens. Also has 20-alpha-HSD activity. Uses preferentially NADH.

• NCBI Gene ID:

  3292

• Swiss Prot:

  P14061

• Accession Number:

  P14061

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This HSD17B1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 227-256 amino acids from the C-terminal region of human HSD17B1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Obesity, Neuroscience, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  35 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  HSD17B1

• NCBI Official Name:

  Estradiol 17-beta-dehydrogenase 1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Canzian, F., et al. Hum. Mol. Genet. 19 (19) :3873-3884 (2010)

• Background Reference 02:

  Liu, C.Y., et al. Carcinogenesis 31 (7) :1259-1263 (2010)

• Background Reference 03:

  Lamp, M., et al. Gynecol. Endocrinol. (2010) In press :

• Background Reference 04:

  Haller, F., et al. J. Mol. Biol. 399 (2) :255-267 (2010)

• Other Product Names:

  Estradiol 17-beta-dehydrogenase 1, 17-beta-hydroxysteroid dehydrogenase type 1, 17-beta-HSD 1, 20 alpha-hydroxysteroid dehydrogenase, 20-alpha-HSD, E2DH, Placental 17-beta-hydroxysteroid dehydrogenase, HSD17B1, E17KSR, EDH17B1, EDH17B2, EDHB17

• Tested Applications:

  WB

• Protein ID:

  313104233

• Physical Properties:

  Liquid