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HSD17B4 Antibody

CAT: 0223-56-474Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-56-474Size:400 µL
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Background
The protein encoded by this gene is a bifunctional enzyme that is involved in the peroxisomal beta-oxidation pathway for fatty acids. It also acts as a catalyst for the formation of 3-ketoacyl-CoA intermediates from both straight-chain and 2-methyl-branched-chain fatty acids. Defects in this gene that affect the peroxisomal fatty acid beta-oxidation activity are a cause of D-bifunctional protein deficiency (DBPD) . An apparent pseudogene of this gene is present on chromosome 8. [provided by RefSeq].
NCBI Gene ID
3295
Swiss Prot
P51659
Accession Number
P51659
Host
Rabbit
Reactivity
Human
Immunogen
This HSD17B4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 341-370 amino acids from the Central region of human HSD17B4.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
80 kDa
Fragment
Rabbit Ig
Symbol
HSD17B4
NCBI Official Name
Peroxisomal multifunctional enzyme type 2
NCBI Organism
Homo sapiens
Background Reference 01
Canzian, F., et al. Hum. Mol. Genet. 19 (19) :3873-3884 (2010)
Background Reference 02
Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)
Background Reference 03
Kashiwayama, Y., et al. J. Biol. Chem. 285 (34) :26315-26325 (2010)
Background Reference 04
Pierce, S.B., et al. Am. J. Hum. Genet. 87 (2) :282-288 (2010)
Other Product Names
Peroxisomal multifunctional enzyme type 2, MFE-2, 17-beta-hydroxysteroid dehydrogenase 4, 17-beta-HSD 4, D-bifunctional protein, DBP, Multifunctional protein 2, MPF-2, (3R) -hydroxyacyl-CoA dehydrogenase, 111n12, Enoyl-CoA hydratase 2, 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA hydratase, HSD17B4, EDH17B4
Tested Applications
WB, IHC-P
Protein ID
1706396
Physical Properties
Liquid

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