G6PD Antibody

CAT: 0223-61-790Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-61-790Size:400 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
G6PD encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly produced from missense mutations, have been described with wide ranging levels of enzyme activity and associated clinical symptoms. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia.
NCBI Gene ID
2539
Swiss Prot
P11413
Accession Number
P11413
Host
Rabbit
Reactivity
Human
Immunogen
This G6PD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 297-326 amino acids from the Central region of human G6PD.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Obesity, Signal Transduction
Purification
This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
59 kDa
Fragment
Rabbit Ig
Symbol
G6PD
NCBI Official Name
Glucose-6-phosphate 1-dehydrogenase
NCBI Organism
Homo sapiens
Background Reference 01
Louicharoen, C., et al. Science 326 (5959) :1546-1549 (2009)
Background Reference 02
Zhong, D.N., et al. Zhongguo Dang Dai Er Ke Za Zhi 11 (12) :970-972 (2009)
Background Reference 03
Tiono, A.B., et al. Am. J. Trop. Med. Hyg. 81 (6) :969-978 (2009)
Other Product Names
Glucose-6-phosphate 1-dehydrogenase, G6PD, G6PD
Tested Applications
WB, IHC-P, Flow
Protein ID
116242483
Physical Properties
Liquid

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