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G6PC Antibody

CAT: 0223-25-939Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-25-939Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
G6PC hydrolyzes glucose-6-phosphate to glucose in the endoplasmic reticulum.It forms with the glucose-6-phosphate transporter (SLC37A4/G6PT) the complex responsible for glucose production through glycogenolysis and gluconeogenesis. Hence, it is the key enzyme in homeostatic regulation of blood glucose levels.Glucose-6-phosphatase is an integral membrane protein of the endoplasmic reticulum that catalyzes the hydrolysis of D-glucose 6-phosphate to D-glucose and orthophosphate. It is a key enzyme in glucose homeostasis, functioning in gluconeogenesis and glycogenolysis. Defects in the enzyme cause glycogen storage disease type I (von Gierke disease) . Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
NCBI Gene ID
2538
Swiss Prot
P35575
Accession Number
NP_000142
Host
Rabbit
Reactivity
Human, Dog
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human G6PC.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Membrane
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. XBL-10410 - Fetal Lung Tissue Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and and may contain up to 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store G6PC antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
40 kDa
Applications Notes
G6PC antibody can be used for detection of G6PC by ELISA at 1:62500. G6PC antibody can be used for detection of G6PC by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
G6PC
NCBI Official Name
Glucose-6-phosphatase, catalytic subunit
NCBI Organism
Homo sapiens
Background Reference 01
Barkaoui, E., J. Inherit. Metab. Dis. 30 (6), 989 (2007) .
Other Product Names
G6PC, G6PT, GSD1a, MGC163350, GSD1, G6PC1
Tested Applications
ELISA, WB
Protein ID
393537031
Physical Properties
Liquid

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