G6PC Antibody

• Background:

  Glucose-6-phosphatase is an integral membrane protein of the endoplasmic reticulum that catalyzes the hydrolysis of D-glucose 6-phosphate to D-glucose and orthophosphate. It is a key enzyme in glucose homeostasis, functioning in gluconeogenesis and glycogenolysis. Defects in the enzyme cause glycogen storage disease type I.

• NCBI Gene ID:

  2538

• Swiss Prot:

  P35575

• Accession Number:

  P35575

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This G6PC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 123-149 amino acids from the Central region of human G6PC.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Cell Cycle, Obesity

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  40 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  G6PC

• NCBI Official Name:

  Glucose-6-phosphatase

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Tu, E., et al. Hum. Pathol. 41 (3) :392-400 (2010)

• Background Reference 02:

  Samuel, V.T., et al. Proc. Natl. Acad. Sci. U.S.A. 106 (29) :12121-12126 (2009)

• Background Reference 03:

  Hu, C., et al. Diabetologia 52 (3) :451-456 (2009)

• Other Product Names:

  Glucose-6-phosphatase, G-6-Pase, G6Pase, Glucose-6-phosphatase alpha, G6Pase-alpha, G6PC, G6PT

• Tested Applications:

  WB, IHC-P, Flow

• Protein ID:

  206729864

• Physical Properties:

  Liquid