KRT82 Antibody

• Background:

  KRT82 is a member of the keratin gene family. As a type II hair keratin, it is a basic protein which heterodimerizes with type I keratins to form hair and nails. The type II hair keratins are clustered in a region of chromosome 12q13 and are grouped into two distinct subfamilies based on structure similarity. One subfamily, consisting of KRTHB1, KRTHB3, and KRTHB6, is highly related. The other less-related subfamily includes KRTHB2, KRTHB4, and KRTHB5. All hair keratins are expressed in the hair follicle; this keratin appears to be a hair cuticle-specific keratin.

• NCBI Gene ID:

  3888

• Swiss Prot:

  Q9NSB4

• Accession Number:

  Q9NSB4

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This KRT82 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 312-341 amino acids from the Central region of human KRT82.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  57 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  KRT82

• NCBI Official Name:

  Keratin, type II cuticular Hb2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) Schweizer, J., et al. J. Cell Biol. 174 (2) :169-174 (2006) Rogers, M.A., et al. J. Invest. Dermatol. 124 (3) :536-544 (2005)

• Other Product Names:

  Keratin, type II cuticular Hb2, Keratin-82, K82, Type II hair keratin Hb2, Type-II keratin Kb22, KRT82, KRTHB2

• Tested Applications:

  WB, IHC-P

• Protein ID:

  148887391

• Physical Properties:

  Liquid