KRT12 Antibody

• Background :

  KRT12 encodes the type I intermediate filament chain keratin 12, expressed in corneal epithelia. Mutations in this gene lead to Meesmann corneal dystrophy.

• NCBI Gene ID :

  3859

• Swiss Prot :

  Q99456

• Accession Number :

  Q99456

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  This KRT12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 442-471 amino acids from the C-terminal region of human KRT12.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Neuroscience, Signal Transduction

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  54 kDa

• Fragment :

  Rabbit Ig

• Symbol :

  KRT12

• NCBI Official Name :

  Keratin, type I cytoskeletal 12

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Clausen, I., et al. Mol. Vis. 16, 954-960 (2010) :

• Background Reference 02 :

  Seto, T., et al. Jpn. J. Ophthalmol. 52 (3) :224-226 (2008)

• Background Reference 03 :

  Nielsen, K., et al. Cornea 27 (1) :100-102 (2008)

• Background Reference 04 :

  Sullivan, L.S., et al. Mol. Vis. 13, 975-980 (2007) :

• Other Product Names :

  Keratin, type I cytoskeletal 12, Cytokeratin-12, CK-12, Keratin-12, K12, KRT12

• Tested Applications :

  WB, IHC-P, Flow

• Protein ID :

  2497269

• Physical Properties :

  Liquid