KRT80 Antibody

CAT: 0223-55-483Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-55-483Size:400 µL
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into epithelial keratins and hair keratins. This gene's expression profile shows that it encodes a type II epithelial keratin, although structurally the encoded protein is more like a type II hair keratin. This protein is involved in cell differentiation, localizing near desmosomal plaques in earlier stages of differentiation but then dispersing throughout the cytoplasm in terminally differentiating cells. The type II keratins are clustered in a region of chromosome 12q13. Two transcript variants encoding two different fully functional isoforms have been found for this gene.
NCBI Gene ID
144501
Swiss Prot
Q6KB66
Accession Number
Q6KB66
Host
Rabbit
Reactivity
Human
Immunogen
This KRT80 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 404-432 amino acids from the C-terminal region of human KRT80.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
51 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
KRT80
NCBI Official Name
Keratin, type II cytoskeletal 80
NCBI Organism
Homo sapiens
Background Reference 01
Langbein, L., et al. J. Biol. Chem. 285 (47) :36909-36921 (2010)
Background Reference 02
Lamesch, P., et al. Genomics 89 (3) :307-315 (2007)
Background Reference 03
Schweizer, J., et al. J. Cell Biol. 174 (2) :169-174 (2006)
Background Reference 04
Rogers, M.A., et al. J. Invest. Dermatol. 124 (3) :536-544 (2005)
Other Product Names
Keratin, type II cytoskeletal 80, Cytokeratin-80, CK-80, Keratin-80, K80, Type-II keratin Kb20, KRT80, KB20
Tested Applications
WB
Protein ID
166218808
Physical Properties
Liquid

Related Products

CatalogName
60-876KRT86 Antibody
62-411KRT10 Antibody
13-105KRT20 Antibody
61-771KRT82 Antibody
25-716KRT10 Antibody
29-769KRT20 Antibody
62-412KRT10 Antibody
23-272KRT10 Antibody
29-684KRT8 Antibody
51-479KRT81 Antibody [3B10-5B10]

Alternative Products

CatalogName
MBS8504686-01KRT80 Antibody
MBS9126028-01KRT80 Polyclonal Antibody
PAab04657Anti-KRT80 antibody
MBS8562482-01KRT80

Popular Products