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KRT72 Antibody

CAT: 0223-60-728Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-60-728Size:400 µL
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Background
Keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells. The type II keratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This gene encodes a type II keratin that is specifically expressed in the inner root sheath of hair follicles. The type II keratins are clustered in a region of chromosome 12q12-q13. Multiple transcript variants encoding different isoforms have been found for this gene.
NCBI Gene ID
140807
Swiss Prot
Q14CN4
Accession Number
Q14CN4
Host
Rabbit
Reactivity
Human
Immunogen
This KRT72 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 313-342 amino acids from the Central region of human KRT72.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
56 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
KRT72
NCBI Official Name
Keratin, type II cytoskeletal 72
NCBI Organism
Homo sapiens
Background Reference 01
Bertheau, P., et al. PLoS Med. (3), E90 (2007) :
Background Reference 02
Schweizer, J., et al. J. Cell Biol. 174 (2) :169-174 (2006)
Background Reference 03
Langbein, L., et al. J. Invest. Dermatol. 120 (4) :512-522 (2003)
Background Reference 04
Porter, R.M., et al. Br. J. Dermatol. 145 (4) :558-568 (2001)
Other Product Names
Keratin, type II cytoskeletal 72, Cytokeratin-72, CK-72, Keratin-72, K72, Type II inner root sheath-specific keratin-K6irs2, Type-II keratin Kb35, KRT72, K6IRS2, KB35, KRT6, KRT6IRS2
Tested Applications
WB
Protein ID
166218813
Physical Properties
Liquid

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