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DCC1 Antibody

CAT: 0223-61-568Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-61-568Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
CHTF18 (MIM 613201), CHTF8 (MIM 613202), and DSCC1 are components of an alternative replication factor C (RFC) (see MIM 600404) complex that loads PCNA (MIM 176740) onto DNA during S phase of the cell cycle (Merkle et al., 2003 [PubMed 12766176]; Bermudez et al., 2003 [PubMed 12930902]) .
NCBI Gene ID
79075
Swiss Prot
Q9BVC3
Accession Number
Q9BVC3
Host
Rabbit
Reactivity
Human
Immunogen
This DCC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 311-339 amino acids from the C-terminal region of human DCC1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
45 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
DSCC1
NCBI Official Name
Sister chromatid cohesion protein DCC1
NCBI Organism
Homo sapiens
Background Reference 01
Murakami, T., et al. J. Biol. Chem. 285 (45) :34608-34615 (2010)
Background Reference 02
Terret, M.E., et al. Nature 462 (7270) :231-234 (2009)
Background Reference 03
Watrin, E., et al. Curr. Biol. 16 (9) :863-874 (2006)
Background Reference 04
Bermudez, V.P., et al. Proc. Natl. Acad. Sci. U.S.A. 100 (18) :10237-10242 (2003)
Other Product Names
Sister chromatid cohesion protein DCC1, Defective in sister chromatid cohesion protein 1 homolog, DSCC1, DCC1
Tested Applications
WB
Protein ID
167012058
Physical Properties
Liquid

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