Mouse Dcc Antibody

• Background :

  Receptor for netrin required for axon guidance. Mediates axon attraction of neuronal growth cones in the developing nervous system upon ligand binding. Its association with UNC5 proteins may trigger signaling for axon repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand. Implicated as a tumor suppressor gene.

• NCBI Gene ID :

  13176

• Swiss Prot :

  P70211

• Accession Number :

  P70211

• Host :

  Rabbit

• Reactivity :

  Mouse

• Immunogen :

  This Mouse Dcc antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1391-1417 amino acids from the C-terminal region of mouse Dcc.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Cell Cycle, Neuroscience

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Homology :

  Predicted species reactivity based on immunogen sequence: Rat

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  158 kDa

• Fragment :

  Rabbit Ig

• Applications Notes :

  For WB starting dilution is: 1:1000

• Symbol :

  Dcc

• NCBI Official Name :

  Netrin receptor DCC

• NCBI Organism :

  Mus musculus

• Other Product Names :

  Netrin receptor DCC, Tumor suppressor protein DCC, Dcc

• Tested Applications :

  WB

• Physical Properties :

  Liquid