SDHA Antibody

• Background:

  Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q) . Can act as a tumor suppressor.

• NCBI Gene ID:

  6389

• Swiss Prot:

  P31040

• Accession Number:

  P31040

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This SDHA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 577-605 amino acids from the C-terminal region of human SDHA.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Cell Cycle, Obesity, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Xenopus, Rat

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  73 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  SDHA

• NCBI Official Name:

  Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Hirawake H., et al. J. Biochem. 116:221-227 (1994) .

• Background Reference 02:

  Morris A.A.M., et al. Biochim. Biophys. Acta 1185:125-128 (1994) .

• Background Reference 03:

  Parfait B., et al. Hum. Genet. 106:236-243 (2000) .

• Background Reference 04:

  Ota T., et al. Nat. Genet. 36:40-45 (2004) .

• Other Product Names:

  Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial, Flavoprotein subunit of complex II, Fp, SDHA, SDH2, SDHF

• Tested Applications:

  WB, IHC-P

• Protein ID:

  1169337

• Physical Properties:

  Liquid