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EIF4EBP2 Antibody

CAT: 0223-60-797Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-60-797Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of the eukaryotic translation initiation factor 4E binding protein family. The gene products of this family bind eIF4E and inhibit translation initiation. However, insulin and other growth factors can release this inhibition via a phosphorylation-dependent disruption of their binding to eIF4E. Regulation of protein production through these gene products have been implicated in cell proliferation, cell differentiation and viral infection.
NCBI Gene ID
1979
Swiss Prot
Q13542
Accession Number
Q13542
Host
Rabbit
Reactivity
Human
Immunogen
This EIF4EBP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 87-115 amino acids from the C-terminal region of human EIF4EBP2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
13 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
EIF4EBP2
NCBI Official Name
Eukaryotic translation initiation factor 4E-binding protein 2
NCBI Organism
Homo sapiens
Background Reference 01
Bailey, S.D., et al. Diabetes Care (2010) In press :
Background Reference 02
Bidinosti, M., et al. J. Biol. Chem. 285 (25) :19402-19408 (2010)
Background Reference 03
Johnatty, S.E., et al. PLoS Genet. (7), E1001016 (2010) :
Background Reference 04
Talmud, P.J., et al. Am. J. Hum. Genet. 85 (5) :628-642 (2009)
Other Product Names
Eukaryotic translation initiation factor 4E-binding protein 2, 4E-BP2, eIF4E-binding protein 2, EIF4EBP2
Tested Applications
WB
Protein ID
34921510
Physical Properties
Liquid

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