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CRYM Antibody

CAT: 0223-60-710Size: 400 µLDry Ice: NoHazardous: No
CAT#: 60-710Size: 400 µL
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PRICE
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Crystallins are separated into two classes: taxon-specific and ubiquitous. The former class is also called phylogenetically-restricted crystallins. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. This gene encodes a taxon-specific crystallin protein that binds NADPH and has sequence similarity to bacterial ornithine cyclodeaminases. The encoded protein does not perform a structural role in lens tissue, and instead it binds thyroid hormone for possible regulatory or developmental roles. Mutations in this gene have been associated with autosomal dominant non-syndromic deafness. Multiple alternatively spliced transcript variants have been found for this gene.
NCBI Gene ID
1428
Swiss Prot
Q14894
Accession Number
Q14894
Host
Rabbit
Reactivity
Mouse
Immunogen
This CRYM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 154-183 amino acids from the Central region of human CRYM.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
34 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
CRYM
NCBI Official Name
Ketimine reductase mu-crystallin
NCBI Organism
Homo sapiens
Background Reference 01
Martins-de-Souza, D., et al.Psychiatr Res (2010) In press :
Background Reference 02
Al-Kafaji, G., et al. Biochem. Biophys. Res. Commun. 391 (4) :1585-1591 (2010)
Background Reference 03
Malinowska, K., et al. Prostate 69 (10) :1109-1118 (2009)
Background Reference 04
Martins-de-Souza, D., et al.Psychiatr Res 43 (11) :978-986 (2009)
Other Product Names
Ketimine reductase mu-crystallin, NADP-regulated thyroid-hormone-binding protein, CRYM, THBP
Tested Applications
WB
Protein ID
2498259
Physical Properties
Liquid

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