CRY1 Antibody

CAT: 0223-79-637Size: 0.1 mgDry Ice: NoHazardous: No
CAT#:0223-79-637Size:0.1 mg
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Background
Blue light-dependent regulator of the circadian feedback loop. Inhibits CLOCK|NPAS2-ARNTL E box-mediated transcription. Acts, in conjunction with CRY2, in maintaining period length and circadian rhythmicity. Has no photolyase activity. Capable of translocating circadian clock core proteins such as PER proteins to the nucleus. May inhibit CLOCK|NPAS2-ARNTL transcriptional activity through stabilizing the unphosphorylated form of ARNTL
NCBI Gene ID
12952
Swiss Prot
Q16526
Accession Number
NP_031797.1
Host
Rabbit
Reactivity
Mouse
Immunogen
CRY1 antibody was raised against a peptide sequence around aa.551~555 (S-Q-G-S-G) derived from Mouse CRY1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Concentration
1 mg/mL
Buffer
Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store antibody at -20˚ C for up to one year.
Calculated Molecular Weight
60 kDa
Specificity
This antibody detects endogenous level of total CRY1 protein.
Applications Notes
Western Blot: 1:500~1:1000
Symbol
Cry1
NCBI Official Name
Cryptochrome 1 (photolyase-like)
NCBI Organism
This antibody was raised against a peptide sequence around aa.551~555 (S-Q-G-S-G) derived from Mouse CRY1.
Background Reference 01
Morioka N, et al. (2010) J Pharmacol Sci. 113 (3) : 234-45. Fonseca F, et al. (2010) Mol Diagn Ther. 14 (3) : 171-8. Stratmann M, et al. (2010) Genes Dev. 24 (12) : 1317-28.
Other Product Names
Phll1, AU020726, AU021000, PHLL1
Tested Applications
WB
Protein ID
6681031
Physical Properties
Liquid

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