CRYZ Antibody

• Background:

  Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. The former class is also called phylogenetically-restricted crystallins. This gene encodes a taxon-specific crystallin protein which has NADPH-dependent quinone reductase activity distinct from other known quinone reductases. It lacks alcohol dehydrogenase activity although by similarity it is considered a member of the zinc-containing alcohol dehydrogenase family. Unlike other mammalian species, in humans, lens expression is low. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. One pseudogene is known to exist.

• NCBI Gene ID:

  1429

• Swiss Prot:

  Q08257

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein containing a sequence corresponding to amino acids 1-329 of human CRYZ (NP_001123514.1) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Neuroscience, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  K-562

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 37kDa

• Fragment:

  IgG

• Applications Notes:

  WB: 1:500 - 1:2000

• Symbol:

  CRYZ

• Positive Control 2:

  Mouse liver

• Positive Control 3:

  Mouse brain

• Positive Control 4:

  Mouse kidney

• Positive Control 5:

  Rat kidney

• NCBI Official Name:

  Crystallin, zeta (quinone reductase)

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  CRYZ, DKFZp779E0834, FLJ41475

• Tested Applications:

  WB

• Physical Properties:

  Liquid