MSX1 Antibody

• Background:

  This gene encodes a member of the muscle segment homeobox gene family. The encoded protein functions as a transcriptional repressor during embryogenesis through interactions with components of the core transcription complex and other homeoproteins. It may also have roles in limb-pattern formation, craniofacial development, particularly odontogenesis, and tumor growth inhibition. Mutations in this gene, which was once known as homeobox 7, have been associated with nonsyndromic cleft lip with or without cleft palate 5, Witkop syndrome, Wolf-Hirschom syndrome, and autosomoal dominant hypodontia.

• NCBI Gene ID:

  4487

• Swiss Prot:

  P28360

• Accession Number:

  P28360

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This MSX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 111-138 amino acids from the Central region of human MSX1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle, Neuroscience, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Bovine

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  31 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  MSX1

• NCBI Official Name:

  Homeobox protein MSX-1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  References for protein:

• Background Reference 02:

  Sliwinski, T., et al. Cancer Epidemiol 34 (5) :652-655 (2010)

• Background Reference 03:

  Nikopensius, T., et al. Birth Defects Res. PartClin. Mol. Teratol. 88 (9) :748-756 (2010)

• Background Reference 04:

  Suazo, J., et al. Am. J. Med. Genet.152A (8), 2011-2016 (2010) :

• Other Product Names:

  Homeobox protein MSX-1, Homeobox protein Hox-7, Msh homeobox 1-like protein, MSX1, HOX7

• Tested Applications:

  WB, IF

• Protein ID:

  557952603

• Physical Properties:

  Liquid