Msx2 Antibody

• Background :

  This gene encodes a member of the muscle segment homeobox gene family. The encoded protein is a transcriptional repressor whose normal activity may establish a balance between survival and apoptosis of neural crest-derived cells required for proper craniofacial morphogenesis. The encoded protein may also have a role in promoting cell growth under certain conditions and may be an important target for the RAS signaling pathways. Mutations in this gene are associated with parietal foramina 1 and craniosynostosis type 2.

• NCBI Gene ID :

  4488

• Swiss Prot :

  P35548

• Accession Number :

  P35548

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  This Msx2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 191-222 amino acids from the C-terminal region of human Msx2.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Cancer, Neuroscience

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  29 kDa

• Fragment :

  Rabbit Ig

• Symbol :

  MSX2

• NCBI Official Name :

  Homeobox protein MSX-2

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Shao, J.S., Ann. N. Y. Acad. Sci. 1117, 40-50 (2007)

• Background Reference 02 :

  Han, J., Mech. Dev. 124 (9-10), 729-745 (2007)

• Background Reference 03 :

  Ghassibe, M., Eur. J. Pediatr. 165 (10), 734-735 (2006)

• Other Product Names :

  Homeobox protein MSX-2, Homeobox protein Hox-8, MSX2, HOX8

• Tested Applications :

  WB, IHC-P

• Protein ID :

  311033429

• Physical Properties :

  Liquid