MSX2 Antibody

• Background:

  This gene encodes a member of the muscle segment homeobox gene family. The encoded protein is a transcriptional repressor whose normal activity may establish a balance between survival and apoptosis of neural crest-derived cells required for proper craniofacial morphogenesis. The encoded protein may also have a role in promoting cell growth under certain conditions and may be an important target for the RAS signaling pathways. Mutations in this gene are associated with parietal foramina 1 and craniosynostosis type 2.

• NCBI Gene ID:

  4488

• Swiss Prot:

  P35548

• Accession Number:

  P35548

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This MSX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 120-148 amino acids from the Central region of human MSX2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Neuroscience

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Chicken, Xenopus, Bovine, Mouse, Rat, Zebrafish

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  29 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  MSX2

• NCBI Official Name:

  Homeobox protein MSX-2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Nikopensius, T., et al. Birth Defects Res. PartClin. Mol. Teratol. 88 (9) :748-756 (2010)

• Background Reference 02:

  Satoh, K., et al. J. Gastroenterol. 45 (7) :763-770 (2010)

• Background Reference 03:

  Doi, T., et al. J. Pediatr. Surg. 45 (6) :1187-1191 (2010)

• Background Reference 04:

  Jagomagi, T., et al. Eur. J. Oral Sci. 118 (3) :213-220 (2010)

• Other Product Names:

  Homeobox protein MSX-2, Homeobox protein Hox-8, MSX2, HOX8

• Tested Applications:

  WB

• Protein ID:

  311033429

• Physical Properties:

  Liquid