MSX2 Antibody

CAT: 0223-57-906Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-57-906Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of the muscle segment homeobox gene family. The encoded protein is a transcriptional repressor whose normal activity may establish a balance between survival and apoptosis of neural crest-derived cells required for proper craniofacial morphogenesis. The encoded protein may also have a role in promoting cell growth under certain conditions and may be an important target for the RAS signaling pathways. Mutations in this gene are associated with parietal foramina 1 and craniosynostosis type 2.
NCBI Gene ID
4488
Swiss Prot
P35548
Accession Number
P35548
Host
Rabbit
Reactivity
Human
Immunogen
This MSX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 120-148 amino acids from the Central region of human MSX2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Neuroscience
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Chicken, Xenopus, Bovine, Mouse, Rat, Zebrafish
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
29 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
MSX2
NCBI Official Name
Homeobox protein MSX-2
NCBI Organism
Homo sapiens
Background Reference 01
Nikopensius, T., et al. Birth Defects Res. PartClin. Mol. Teratol. 88 (9) :748-756 (2010)
Background Reference 02
Satoh, K., et al. J. Gastroenterol. 45 (7) :763-770 (2010)
Background Reference 03
Doi, T., et al. J. Pediatr. Surg. 45 (6) :1187-1191 (2010)
Background Reference 04
Jagomagi, T., et al. Eur. J. Oral Sci. 118 (3) :213-220 (2010)
Other Product Names
Homeobox protein MSX-2, Homeobox protein Hox-8, MSX2, HOX8
Tested Applications
WB
Protein ID
311033429
Physical Properties
Liquid

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