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MSX2 Antibody

CAT: 0223-28-805Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-28-805Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
MSX2 is a member of the muscle segment homeobox gene family. The protein is a transcriptional repressor whose normal activity may establish a balance between survival and apoptosis of neural crest-derived cells required for proper craniofacial morphogenesis. The protein may also have a role in promoting cell growth under certain conditions and may be an important target for the RAS signaling pathways. Mutations in this gene are associated with parietal foramina 1 and craniosynostosis type 2.This gene encodes a member of the muscle segment homeobox gene family. The encoded protein is a transcriptional repressor whose normal activity may establish a balance between survival and apoptosis of neural crest-derived cells required for proper craniofacial morphogenesis. The encoded protein may also have a role in promoting cell growth under certain conditions and may be an important target for the RAS signaling pathways. Mutations in this gene are associated with parietal foramina 1 and craniosynostosis type 2.
NCBI Gene ID
4488
Swiss Prot
P35548
Accession Number
NP_002440
Host
Rabbit
Reactivity
Human, Dog
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MSX2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Transcription, Cancer
Purification
Antibody is purified by protein A chromatography method.
Positive Control
Cat. No. 1205 - Jurkat Cell Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store MSX2 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
29 kDa
Applications Notes
MSX2 antibody can be used for detection of MSX2 by ELISA at 1:312500. MSX2 antibody can be used for detection of MSX2 by western blot at 1.25 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
MSX2
NCBI Official Name
Msh homeobox 2
NCBI Organism
Homo sapiens
Background Reference 01
Le (2006) Calcif. Tissue Int. 78 (2), 98-102.
Other Product Names
MSX2, FPP, MSH, PFM, CRS2, HOX8, PFM1
Tested Applications
ELISA, WB, IHC
Protein ID
27886557
Physical Properties
Liquid

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