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KATNA1 Antibody

CAT: 0223-60-126Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-60-126Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Microtubules, polymers of alpha and beta tubulin subunits, form the mitotic spindle of a dividing cell and help to organize membranous organelles during interphase. Katanin is a heterodimer that consists of a 60 kDa ATPase (p60 subunit A 1) and an 80 kDa accessory protein (p80 subunit B 1) . The p60 subunit acts to sever and disassemble microtubules, while the p80 subunit targets the enzyme to the centrosome. This gene encodes the p80 subunit. This protein is a member of the AAA family of ATPases. [provided by RefSeq].
NCBI Gene ID
11104
Swiss Prot
O75449
Accession Number
O75449
Host
Rabbit
Reactivity
Human
Immunogen
This KATNA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 59-85 amino acids from the N-terminal region of human KATNA1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Neuroscience
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Monkey
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
56 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
KATNA1
NCBI Official Name
Katanin p60 ATPase-containing subunit A1 {ECO:0000255|HAMAP-Rule:MF_03023}
NCBI Organism
Homo sapiens
Background Reference 01
Olson, J.E., et al. Breast Cancer Res. Treat. (2010) In press :
Background Reference 02
Iwaya, N., et al. J. Biol. Chem. 285 (22) :16822-16829 (2010)
Background Reference 03
Sudo, H., et al. Hum. Mol. Genet. 17 (16) :2524-2540 (2008)
Background Reference 04
Mungall, A.J., et al. Nature 425 (6960) :805-811 (2003)
Other Product Names
Katanin p60 ATPase-containing subunit A1 {ECO:0000255|HAMAP-Rule:MF_03023}, Katanin p60 subunit A1 {ECO:0000255|HAMAP-Rule:MF_03023}, 3643 {ECO:0000255|HAMAP-Rule:MF_03023}, p60 katanin {ECO:0000255|HAMAP-Rule:MF_03023}, KATNA1 {ECO:0000255|HAMAP-Rule:MF_03023}
Tested Applications
WB
Physical Properties
Liquid

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