KATNA1 Antibody

• Background:

  Microtubules, polymers of alpha and beta tubulin subunits, form the mitotic spindle of a dividing cell and help to organize membranous organelles during interphase. Katanin is a heterodimer that consists of a 60 kDa ATPase (p60 subunit A 1) and an 80 kDa accessory protein (p80 subunit B 1) . The p60 subunit acts to sever and disassemble microtubules, while the p80 subunit targets the enzyme to the centrosome. This gene encodes the p80 subunit. This protein is a member of the AAA family of ATPases. [provided by RefSeq].

• NCBI Gene ID:

  11104

• Swiss Prot:

  O75449

• Accession Number:

  O75449

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This KATNA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 59-85 amino acids from the N-terminal region of human KATNA1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle, Neuroscience

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Monkey

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  56 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  KATNA1

• NCBI Official Name:

  Katanin p60 ATPase-containing subunit A1 {ECO:0000255|HAMAP-Rule:MF_03023}

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Olson, J.E., et al. Breast Cancer Res. Treat. (2010) In press :

• Background Reference 02:

  Iwaya, N., et al. J. Biol. Chem. 285 (22) :16822-16829 (2010)

• Background Reference 03:

  Sudo, H., et al. Hum. Mol. Genet. 17 (16) :2524-2540 (2008)

• Background Reference 04:

  Mungall, A.J., et al. Nature 425 (6960) :805-811 (2003)

• Other Product Names:

  Katanin p60 ATPase-containing subunit A1 {ECO:0000255|HAMAP-Rule:MF_03023}, Katanin p60 subunit A1 {ECO:0000255|HAMAP-Rule:MF_03023}, 3643 {ECO:0000255|HAMAP-Rule:MF_03023}, p60 katanin {ECO:0000255|HAMAP-Rule:MF_03023}, KATNA1 {ECO:0000255|HAMAP-Rule:MF_03023}

• Tested Applications:

  WB

• Physical Properties:

  Liquid