KAT2A Antibody

• Background :

  KAT2A, or GCN5, is a histone acetyltransferase (HAT) that functions primarily as a transcriptional activator. It also functions as a repressor of NF-kappa-B (see MIM 164011) by promoting ubiquitination of the NF-kappa-B subunit RELA (MIM 164014) in a HAT-independent manner (Mao et al., 2009 [PubMed 19339690]) .

• NCBI Gene ID :

  2648

• Swiss Prot :

  Q92830

• Accession Number :

  Q92830

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  This KAT2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 611-638 amino acids from the C-terminal region of human KAT2A.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Other

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Homology :

  Predicted species reactivity based on immunogen sequence: Mouse

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  94 kDa

• Fragment :

  Rabbit Ig

• Applications Notes :

  For WB starting dilution is: 1:1000

• Symbol :

  KAT2A

• NCBI Official Name :

  Histone acetyltransferase KAT2A

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Terreni, M., et al. Retrovirology 7, 18 (2010) :

• Background Reference 02 :

  Atanassov, B.S., et al. Mol. Cell 35 (3) :352-364 (2009)

• Background Reference 03 :

  Kelly, T.J., et al. J. Biol. Chem. 284 (30) :19945-19952 (2009)

• Background Reference 04 :

  Mao, X., et al. Genes Dev. 23 (7) :849-861 (2009)

• Other Product Names :

  Histone acetyltransferase KAT2A, General control of amino acid synthesis protein 5-like 2, Histone acetyltransferase GCN5, HsGCN5, Lysine acetyltransferase 2A, STAF97, KAT2A, GCN5, GCN5L2, HGCN5

• Tested Applications :

  WB

• Protein ID :

  209572743

• Physical Properties :

  Liquid