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KATNB1 Antibody

CAT: 0223-58-590Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-58-590Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Microtubules, polymers of alpha and beta tubulin subunits, form the mitotic spindle of a dividing cell and help to organize membranous organelles during interphase. Katanin is a heterodimer that consists of a 60 kDa ATPase (p60 subunit A 1) and an 80 kDa accessory protein (p80 subunit B 1) . The p60 subunit acts to sever and disassemble microtubules, while the p80 subunit targets the enzyme to the centrosome. Katanin is a member of the AAA family of ATPases.
NCBI Gene ID
10300
Swiss Prot
Q9BVA0
Accession Number
Q9BVA0
Host
Rabbit
Reactivity
Human
Immunogen
This KATNB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 331-359 amino acids from the Central region of human KATNB1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
72 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
KATNB1
NCBI Official Name
Katanin p80 WD40 repeat-containing subunit B1 {ECO:0000255|HAMAP-Rule:MF_03022}
NCBI Organism
Homo sapiens
Background Reference 01
Olson, J.E., et al. Breast Cancer Res. Treat. (2010) In press :
Background Reference 02
Cummings, C.M., et al. J. Biol. Chem. 284 (17) :11663-11675 (2009)
Background Reference 03
Sudo, H., et al. Hum. Mol. Genet. 17 (16) :2524-2540 (2008)
Background Reference 04
Olsen, J.V., et al. Cell 127 (3) :635-648 (2006)
Other Product Names
Katanin p80 WD40 repeat-containing subunit B1 {ECO:0000255|HAMAP-Rule:MF_03022}, Katanin p80 subunit B1 {ECO:0000255|HAMAP-Rule:MF_03022}, p80 katanin {ECO:0000255|HAMAP-Rule:MF_03022}, KATNB1 {ECO:0000255|HAMAP-Rule:MF_03022}
Tested Applications
WB
Protein ID
60390213
Physical Properties
Liquid

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