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CRYBB3 Antibody

CAT: 0223-59-907Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-59-907Size:400 µL
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PRICE
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families; beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Beta-crystallins, the most heterogeneous, differ by the presence of the C-terminal extension (present in the basic group, none in the acidic group) . Beta-crystallins form aggregates of different sizes and are able to self-associate to form dimers or to form heterodimers with other beta-crystallins. This gene, a beta basic group member, is part of a gene cluster with beta-A4, beta-B1, and beta-B2. [provided by RefSeq].
NCBI Gene ID
1417
Swiss Prot
P26998
Accession Number
P26998
Host
Rabbit
Reactivity
Human
Immunogen
This CRYBB3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 179-207 amino acids from the C-terminal region of human CRYBB3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
24 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
CRYBB3
NCBI Official Name
Beta-crystallin B3
NCBI Organism
Homo sapiens
Background Reference 01
Muller, C., et al. Anim. Genet. 39 (1) :87-88 (2008)
Background Reference 02
Wu, C., et al. Proteomics 7 (11) :1775-1785 (2007)
Background Reference 03
Riazuddin, S.A., et al. Invest. Ophthalmol. Vis. Sci. 46 (6) :2100-2106 (2005)
Background Reference 04
Collins, J.E., et al. Genome Biol. (10), R84 (2004) :
Other Product Names
Beta-crystallin B3, Beta-B3 crystallin, Beta-crystallin B3, N-terminally processed, CRYBB3, CRYB3
Tested Applications
WB
Protein ID
311033476
Physical Properties
Liquid

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