CRYBA1 Antibody

CAT: 0223-56-382Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-56-382Size:400 µL
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families; beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Beta-crystallins, the most heterogeneous, differ by the presence of the C-terminal extension (present in the basic group, none in the acidic group) . Beta-crystallins form aggregates of different sizes and are able to self-associate to form dimers or to form heterodimers with other beta-crystallins. This gene, a beta acidic group member, encodes two proteins (crystallin, beta A3 and crystallin, beta A1) from a single mRNA, the latter protein is 17 aa shorter than crystallin, beta A3 and is generated by use of an alternate translation initiation site. Deletion of exons 3 and 4 causes the autosomal dominant disease 'zonular cataract with sutural opacities'.
NCBI Gene ID
1411
Swiss Prot
P05813
Accession Number
P05813
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
This CRYBA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 104-133 amino acids from the Central region of human CRYBA1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
25 kDa
Fragment
Rabbit Ig
Symbol
CRYBA1
NCBI Official Name
Beta-crystallin A3
NCBI Organism
Homo sapiens
Background Reference 01
Xu, J., et al. Mol. Vis. 16, 438-444 (2010) :
Background Reference 02
Gu, Z., et al. Mol. Vis. 16, 154-160 (2010) :
Background Reference 03
Srivastava, K., et al. Biochemistry 48 (30) :7179-7189 (2009)
Background Reference 04
Gupta, R., et al. J. Biol. Chem. 284 (27) :18481-18492 (2009)
Other Product Names
Beta-crystallin A3, Beta-crystallin A3, isoform A1, Delta4 form, Beta-crystallin A3, isoform A1, Delta7 form, Beta-crystallin A3, isoform A1, Delta8 form, CRYBA1, CRYB1
Tested Applications
WB, IHC-P
Protein ID
2506317
Physical Properties
Liquid

Related Products

CatalogName
18-728CRYBB1 Antibody
58-785CRYBA4 Antibody
19-740CRYBB2 Antibody
59-907CRYBB3 Antibody
58-977CRYZL1 Antibody
60-696CRYAA Antibody
19-816CRYAA Antibody
30-376CRYAB Antibody
57-208CRYAB Antibody
15-156CRYAB Antibody

Alternative Products

CatalogName
CSB-PA006009LA01HU-01CRYBA1 Antibody
MBS9203274-01CRYBA1 Antibody (Center)
E55A04913CRYBA1 Polyclonal Antibody
MBS8322839-01Anti-CRYBA1 Antibody
MBS8561293-01CRYBA1

Popular Products