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MARCH10 Antibody

CAT: 0223-59-249Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-59-249Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
MARCH10 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19) . MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments (Morokuma et al., 2007 [PubMed 17604280]) .
NCBI Gene ID
162333
Swiss Prot
Q8NA82
Accession Number
Q8NA82
Host
Rabbit
Reactivity
Human
Immunogen
This MARCH10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 248-274 amino acids from the Central region of human MARCH10.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
91 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
MARCH10
NCBI Official Name
Probable E3 ubiquitin-protein ligase MARCH10
NCBI Organism
Homo sapiens
Background Reference 01
Yoshida, T., et al. Int. J. Mol. Med. 25 (4) :649-656 (2010)
Background Reference 02
Oguri, M., et al. Am. J. Hypertens. 23 (1) :70-77 (2010)
Background Reference 03
Yoshida, T., et al. Int. J. Mol. Med. 24 (4) :539-547 (2009)
Background Reference 04
Morokuma, Y., et al. J. Biol. Chem. 282 (34) :24806-24815 (2007)
Other Product Names
Probable E3 ubiquitin-protein ligase MARCH10, 632-, Membrane-associated RING finger protein 10, Membrane-associated RING-CH protein X, MARCH-X, RING finger protein 190, MARCH10, RNF190
Tested Applications
WB
Protein ID
296439307
Physical Properties
Liquid

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