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MARCH1 Antibody

CAT: 0223-25-837Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0223-25-837Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
MARCH1 is an E3 ubiquitin-protein ligase that may mediate ubiquitination of TFRC, CD86 and FAS, and promote their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.
NCBI Gene ID
55016
Swiss Prot
Q8TCQ1-2
Accession Number
NP_060393
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MARCH1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Membrane
Purification
Antibody is purified by peptide affinity chromatography method.
Positive Control
Cat. No. XBL-10413 - Fetal Skeletal Muscle Tissue Lysate
Concentration
Batch dependent
Buffer
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
For short periods of storage (days) store at 4˚ C. For longer periods of storage, store MARCH1 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.
Calculated Molecular Weight
31 kDa
Applications Notes
MARCH1 antibody can be used for detection of 40238 by ELISA at 1:1562500. MARCH1 antibody can be used for detection of 40238 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Symbol
MARCH1
NCBI Official Name
Membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase
NCBI Organism
Homo sapiens
Background Reference 01
De (2008) Proc. Natl. Acad. Sci. U.S.A. 105 (9), 3491-3496.
Other Product Names
MARCH1, DKFZp564M1682, FLJ20668, MARCH-I, RNF171
Tested Applications
ELISA, WB
Protein ID
8923613
Physical Properties
Liquid

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