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MARCH11 Antibody

CAT: 0223-57-285Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-57-285Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
MARCH11 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19) . These enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their intracellular transport. March11 appears to have a role in ubiquitin-mediated protein sorting in the trans-Golgi network (TGN) -multivesicular body (MVB) transport pathway (Morokuma et al., 2007 [PubMed 17604280]) .
NCBI Gene ID
441061
Swiss Prot
A6NNE9
Accession Number
A6NNE9
Host
Rabbit
Reactivity
Human
Immunogen
This MARCH11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 308-337 amino acids from the C-terminal region of human MARCH11.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Cell Cycle
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
44 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
MARCH11
NCBI Official Name
E3 ubiquitin-protein ligase MARCH11
NCBI Organism
Homo sapiens
Background Reference 01
Rose, J. Phd, et al. Mol. Med. (2010) In press :
Background Reference 02
Morokuma, Y., et al. J. Biol. Chem. 282 (34) :24806-24815 (2007)
Other Product Names
E3 ubiquitin-protein ligase MARCH11, 632-, Membrane-associated RING finger protein 11, Membrane-associated RING-CH protein XI, MARCH-XI, MARCH11
Tested Applications
WB
Physical Properties
Liquid

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