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MARCH7 Antibody

CAT: 0223-58-601Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-58-601Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
MARCH7 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19) . MARCH proteins add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments (Bartee et al., 2004 [PubMed 14722266]) .
NCBI Gene ID
64844
Swiss Prot
Q9H992
Accession Number
Q9H992
Host
Rabbit
Reactivity
Human
Immunogen
This MARCH7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 67-95 amino acids from the N-terminal region of human MARCH7.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
78 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
MARCH7
NCBI Official Name
E3 ubiquitin-protein ligase MARCH7
NCBI Organism
Homo sapiens
Background Reference 01
Szigyarto, C.A., et al. J. Histochem. Cytochem. 58 (4) :301-308 (2010)
Background Reference 02
Nathan, J.A., et al. Traffic 9 (7) :1130-1145 (2008)
Background Reference 03
Muthukumarana, P.A., et al. Int. Immunopharmacol. (13-14), 1993-2001 (2006) :
Background Reference 04
Flierman, D., et al. Proc. Natl. Acad. Sci. U.S.A. 103 (31) :11589-11594 (2006)
Other Product Names
E3 ubiquitin-protein ligase MARCH7, 632-, Axotrophin, Membrane-associated RING finger protein 7, Membrane-associated RING-CH protein VII, MARCH-VII, RING finger protein 177, MARCH7, AXOT, RNF177
Tested Applications
WB
Protein ID
74762745
Physical Properties
Liquid

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