Mouse Tgfbr2 Antibody

• Background:

  On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for TGF-beta.

• NCBI Gene ID:

  21813

• Swiss Prot:

  Q62312

• Accession Number:

  Q62312

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This Mouse Tgfbr2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 548-575 amino acids from the C-terminal region of mouse Tgfbr2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  67 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  Tgfbr2

• NCBI Official Name:

  TGF-beta receptor type-2

• NCBI Organism:

  Mus musculus

• Background Reference 01:

  Droguett, R., et al. Exp. Cell Res. 316 (15) :2487-2503 (2010)

• Background Reference 02:

  Robson, A., et al. Dev. Dyn. 239 (9) :2435-2442 (2010)

• Background Reference 03:

  Moreno, S.G., et al. Dev. Biol. 342 (1) :74-84 (2010)

• Background Reference 04:

  Ouyang, W., et al. Immunity 32 (5) :642-653 (2010)

• Other Product Names:

  TGF-beta receptor type-2, TGFR-2, TGF-beta type II receptor, Transforming growth factor-beta receptor type II, TGF-beta receptor type II, TbetaR-II, Tgfbr2

• Tested Applications:

  WB

• Physical Properties:

  Liquid