TGFBR2 Antibody

CAT: 0223-14-143Size: 100 µLDry Ice: NoHazardous: No
CAT#:0223-14-143Size:100 µL
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
This gene encodes a member of the Ser/Thr protein kinase family and the TGFB receptor subfamily. The encoded protein is a transmembrane protein that has a protein kinase domain, forms a heterodimeric complex with another receptor protein, and binds TGF-beta. This receptor/ligand complex phosphorylates proteins, which then enter the nucleus and regulate the transcription of a subset of genes related to cell proliferation. Mutations in this gene have been associated with Marfan Syndrome, Loeys-Deitz Aortic Aneurysm Syndrome, and the development of various types of tumors. Alternatively spliced transcript variants encoding different isoforms have been characterized.
NCBI Gene ID
7048
Swiss Prot
P37173
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 23-280 of human TGFBR2 (NP_003233.4) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Signal Transduction, Stem Cell
Purification
Affinity purification
Positive Control
Mouse spleen
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 85kDa
Fragment
IgG
Symbol
TGFBR2
Positive Control 2
Rat lung
NCBI Official Name
Transforming growth factor, beta receptor II (70/80kDa)
NCBI Organism
Homo sapiens
Other Product Names
TGFBR2, HNPCC6, MFS2, RIIC, Tbeta, AAT3, FAA3, LDS1B, LDS2B, TAAD2, TGFR-2, TGFbeta-RII
Tested Applications
WB, IHC, IF
Physical Properties
Liquid

Related Products

CatalogName
46-907TGFBR3 Antibody
13-260TGFBR1 Antibody
16-823TGFBR1 Antibody
13-224TGFBR3 Antibody
42-356TGFBR1 Antibody
16-502TGFB2 Antibody
19-116TGFB2 Antibody
57-980Mouse Tgfbr1 Antibody
XG-6171TGFb1 Antibody
42-298TGFBI Antibody

Alternative Products

CatalogName
GWB-AD8026TGFBR2 Antibody

Popular Products