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Mouse Tgfbr1 Antibody

CAT: 0223-57-980Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-57-980Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for TGF-beta.
NCBI Gene ID
21812
Swiss Prot
Q64729
Accession Number
Q64729
Host
Rabbit
Reactivity
Mouse
Immunogen
This Mouse Tgfbr1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 141-169 amino acids from the Central region of mouse Tgfbr1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Human, Pig, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
56 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
Tgfbr1
NCBI Official Name
TGF-beta receptor type-1
NCBI Organism
Mus musculus
Background Reference 01
Ghoreschi, K., et al. Nature 467 (7318) :967-971 (2010)
Background Reference 02
Kel, J.M., et al. J. Immunol. 185 (6) :3248-3255 (2010)
Background Reference 03
Droguett, R., et al. Exp. Cell Res. 316 (15) :2487-2503 (2010)
Background Reference 04
Moreno, S.G., et al. Dev. Biol. 342 (1) :74-84 (2010)
Other Product Names
TGF-beta receptor type-1, TGFR-1, ESK2, Transforming growth factor-beta receptor type I, TGF-beta receptor type I, TbetaR-I, Tgfbr1
Tested Applications
WB
Physical Properties
Liquid

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